Location History:
- Sunnyvale, CA (US) (2010)
- San Diego, CA (US) (2003 - 2013)
Company Filing History:
Years Active: 2003-2013
Title: Kevin P. Lowitz: Innovator in G Protein-Coupled Receptor Research
Introduction
Kevin P. Lowitz is a prominent inventor based in San Diego, California. He has made significant contributions to the field of biochemistry, particularly in the area of G protein-coupled receptors (GPCRs). With a total of three patents to his name, Lowitz's work has the potential to impact therapeutic approaches for various metabolic disorders.
Latest Patents
One of Lowitz's latest patents is focused on "Constitutively activated human G protein coupled receptors." This invention relates to transmembrane receptors, specifically orphan GPCRs, and includes mutated versions of these receptors that exhibit constitutive activity. Another notable patent is titled "Human G protein-coupled receptors for metabolic-related disorders." This invention outlines methods for identifying candidate compounds that modulate GPCRs, particularly those that are coupled to Gi and lower intracellular cAMP levels. These GPCRs are expressed by adipocytes and play a role in inhibiting intracellular lipolysis. The agonists developed from this research are aimed at treating metabolic-related disorders such as dyslipidemia, atherosclerosis, and type 2 diabetes.
Career Highlights
Kevin P. Lowitz is currently associated with Arena Pharmaceuticals, Inc., where he continues to advance his research in GPCRs. His work is crucial in developing therapeutic agents that can address significant health issues related to metabolism.
Collaborations
Lowitz has collaborated with notable colleagues in his field, including Dominic P. Behan and Derek T. Chalmers. These collaborations have further enriched his research and contributed to the advancement of knowledge in GPCR-related therapies.
Conclusion
Kevin P. Lowitz is a key figure in the innovation of G protein-coupled receptor research, with patents that hold promise for treating metabolic disorders. His contributions to the field are invaluable and continue to pave the way for future advancements in therapeutic solutions.