Company Filing History:
Years Active: 2001-2006
Title: Kevin Lustig: Innovator in Nuclear Hormone Receptor Research
Introduction
Kevin Lustig is a notable inventor based in South San Francisco, CA (US). He has made significant contributions to the field of nuclear hormone receptor research, holding a total of 3 patents. His work focuses on developing methods for identifying modulators of nuclear hormone receptor function, which has important implications for drug discovery and therapeutic development.
Latest Patents
Lustig's latest patents include innovative methods for conducting nuclear hormone receptor drug screens. These methods involve forming a mixture that includes a nuclear hormone receptor, a peptide sensor, and a candidate agent, excluding any natural coactivator protein of the receptor. The process measures agent-biased binding of the sensor to the receptor and compares it with unbiased binding. The sensor is designed to provide direct, in vitro binding under specific assay conditions. In particular embodiments, the sensor features an amphipathic alpha helix nuclear hormone interacting domain and is present at sub-micromolar concentrations. The binding reaction occurs in solution, and the sensor is equipped with a fluorescent label, allowing for the detection of fluorescence polarization during the measuring step.
Career Highlights
Throughout his career, Kevin Lustig has worked with prominent companies in the biotechnology sector, including Tularik Limited and Amgen Inc. His experience in these organizations has contributed to his expertise in nuclear hormone receptor research and drug development.
Collaborations
Lustig has collaborated with notable colleagues such as Bei Shan and Patrick A Baeuerle. These partnerships have likely enhanced his research capabilities and broadened the impact of his work in the field.
Conclusion
Kevin Lustig is a distinguished inventor whose work in nuclear hormone receptor research has led to valuable patents and advancements in drug discovery. His contributions continue to influence the scientific community and pave the way for future innovations.