Kevin L Facchine

Title: Kevin L Facchine: Innovator in Cationic Lipids

Introduction

Kevin L Facchine is a notable inventor based in Raleigh, NC (US). He has made significant contributions to the field of biochemistry, particularly in the development of cationic lipids. His work focuses on creating new compounds that facilitate the transfer of nucleic acids and peptides into cells, which has important implications for gene therapy and drug delivery.

Latest Patents

Kevin L Facchine holds a patent for his invention related to cationic lipids. The patent describes new cationic lipids and intermediates in their synthesis that are useful for transfecting nucleic acids or peptides into prokaryotic or eukaryotic cells. The lipids consist of one or two substituted arginine, lysine, or ornithine residues, or derivatives thereof, linked to a lipophilic moiety. These lipids form complexes when mixed with polyanions such as nucleic acids or peptides, allowing for efficient transfer into cells without significant toxicity.

Career Highlights

Kevin is currently employed at Gilead Sciences, Inc., where he continues to advance his research in the field of biochemistry. His work has contributed to the understanding and application of cationic lipids in various biomedical contexts.

Collaborations

Some of his notable coworkers include Randolph B DePrince and George S Lewis, who have collaborated with him on various projects related to his research.

Conclusion

Kevin L Facchine's innovative work in cationic lipids represents a significant advancement in the field of biochemistry. His contributions have the potential to impact gene therapy and drug delivery systems positively.