Port Matilda, PA, United States of America

Kenneth M Merz, Jr


Average Co-Inventor Count = 2.2

ph-index = 2

Forward Citations = 22(Granted Patents)


Location History:

  • State College, PA (US) (2006)
  • Yardley, PA (US) (2007)
  • Port Matilda, PA (US) (2005 - 2011)

Company Filing History:


Years Active: 2005-2011

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4 patents (USPTO):Explore Patents

Title: Innovations of Kenneth M Merz, Jr.

Introduction

Kenneth M Merz, Jr. is a notable inventor based in Port Matilda, PA (US). He has made significant contributions to the field of computational drug design, holding a total of 4 patents. His work primarily focuses on the intersection of quantum mechanics and molecular interactions, providing innovative solutions for drug development.

Latest Patents

One of his latest patents is a quantum mechanics-based method for scoring protein-ligand interactions. This invention offers a groundbreaking approach to predicting binding affinities using quantum mechanical Hamiltonians and a combined quantum mechanical/molecular mechanical approach. It also incorporates Poisson-Boltzmann-based solvation methods. The method allows for the comparison of calculated binding affinities to experimental values, enhancing the accuracy of predictions. This innovation serves as a powerful tool in computational drug design, enabling lead optimization for protein-ligand complexes.

Another significant patent involves one-dimensional molecular representations. In this invention, molecules are represented as one-dimensional strings of atoms, which allows for the assessment of chemical behavior similarity. This method provides a new perspective on molecular interactions and their implications in various chemical processes.

Career Highlights

Throughout his career, Kenneth has worked with prominent organizations such as Accelrys Software, Inc. and The Penn State Research Foundation. His experience in these institutions has contributed to his expertise in computational chemistry and drug design.

Collaborations

Kenneth has collaborated with notable individuals in his field, including David J Diller and Kaushik Raha. These collaborations have further enriched his research and innovations.

Conclusion

Kenneth M Merz, Jr. continues to be a significant figure in the realm of computational drug design, with his innovative patents paving the way for advancements in the field. His contributions are vital for the future of drug development and molecular interactions.

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