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For the Inventor, By the Inventor

Menlo Park, CA, United States of America

Kenneth E Rubenstein

This inventor holds 15 USPTO granted patents, primarily in Enzyme Immunoassays. Top assignee: Syva Company. Active years: 1976-1983.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Kenneth E Rubenstein. Retrieved from https://idiyas.com/inventor/kenneth-e-rubenstein

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Calculating rank
USPTO Granted Patents = 15

% Patents Active = 100.0

Average Co-Inventor Count = 2.0

ph-index = 14

Forward Citations = 751(Granted Patents)


Location History:

  • Palo Alto, CA (US) (1976 - 1978)
  • Menlo Park, CA (US) (1977 - 1983)

Company Filing History:

goldMedal15 out of 104 
 
Syva Company
 patents

Years Active: 1976-1983

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Areas of Expertise:
Enzyme Immunoassays
Amplification Compounds
Steric Hindrance
Antibody Detection
Corticosteroids
Androgens
Malate Dehydrogenase
Lysozyme Conjugates
Cardiac Glycosides
Diazepam Conjugates
Iodothyronine
Ecgonine Analogs
15 patents (USPTO):Explore Patents
1. 4423143 - .beta.-D-Galactosidase conjugate for enzyme immunoassays (1983-12-27),
2. 4376825 - Enzyme amplification compounds for assays for androgens (1983-03-15),
3. 4282325 - Enzyme bound corticosteroids (1981-08-04),
4. 4203802 - Inhibitable enzyme amplification assay (1980-05-20),
5. 4191613 - Malate dehydrogenase conjugates for enzyme immunoassays (1980-03-04),
6. 4190496 - Homogeneous enzyme assay for antibodies (1980-02-26),
7. 4130462 - Receptor steric hindrance immunoassay for receptor determination (1978-12-19),
8. 4067774 - Compounds for enzyme amplification assay (1978-01-10),
9. 4065354 - Lysozyme conjugates for enzyme immunoassays (1977-12-27),
10. 4046636 - Diazepam enzyme conjugates (1977-09-06),
11. 4040907 - Iodothyronine enzyme conjugates (1977-08-09),
12. 4039385 - Cardiac glycoside enzyme conjugates (1977-08-02),
13. 3975237 - Compounds for enzyme amplification assay - - ecgonine analogs (1976-08-17),
14. 3966556 - Compounds for enzyme amplification assay methadone analogs (1976-06-29),
15. 3935074 - Antibody steric hindrance immunoassay with two antibodies (1976-01-27),

Title: Kenneth E. Rubenstein: A Pioneer in Enzyme Immunoassays

Introduction

Kenneth E. Rubenstein, an accomplished inventor based in Menlo Park, California, has made significant contributions to the field of enzyme immunoassays. With an impressive portfolio of 15 patents, Rubenstein continues to innovate within the realm of biological assays, showcasing his expertise and dedication to advancing scientific knowledge.

Latest Patents

Rubenstein's latest patents demonstrate his focus on enhancing the sensitivity and reliability of immunoassays. One such patent is the **β-D-Galactosidase Conjugate for Enzyme Immunoassays**, which involves the conjugation of β-D-Galactosidase with analytes. This method allows for a quantitative determination of the analyte by comparing the resulting enzymatic activity with standard assay media.

Another notable patent is the **Enzyme Amplification Compounds for Assays for Androgens**. This innovative approach employs a modified enzyme to amplify the detection of specific organic materials. By utilizing receptors specific to ligands and forming an 'enzyme-bound-ligand', Rubenstein's method provides an exceedingly sensitive means of assaying for ligands, greatly enhancing detection capabilities in various biological applications.

Career Highlights

Rubenstein's work is closely associated with Syva Company, a leader in developing diagnostic assays. His innovative approaches and patented technologies have had a lasting impact on the company's product offerings and have paved the way for advancements in clinical diagnostics.

Collaborations

Throughout his career, Rubenstein has collaborated with notable colleagues, including Edwin F. Ullman and Richard K. Leute. These partnerships have fostered a rich exchange of ideas and have contributed to the development of cutting-edge technologies within the field of biochemistry and immunoassays.

Conclusion

Kenneth E. Rubenstein stands out as a significant figure in the realm of enzyme immunoassays. His patents and collaborations continue to shape the landscape of biological assays, ensuring that advancements in this field persist. With a commitment to innovation, Rubenstein's work not only benefits the scientific community but also enhances diagnostic capabilities worldwide.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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