This inventor holds 1 USPTO granted patent and 6 published patent applications. Top assignee: Case Western Reserve University. Active years: 2020.
Company Filing History:
Years Active: 2020
Title: Innovations in Cardiac Failure Prediction by Kenneth B. Margulies
Introduction
Kenneth B. Margulies is an accomplished inventor based in Villanova, PA (US). He has made significant contributions to the field of cardiac health through his innovative patent. His work focuses on utilizing advanced technology to predict cardiac failure, which can have profound implications for patient care.
Latest Patents
Kenneth B. Margulies holds a patent for a "Histomorphometric classifier to predict cardiac failure from whole-slide hematoxylin and eosin stained images." This invention employs methods, apparatus, and other embodiments to predict heart failure from whole-slide images (WSIs) of cardiac histopathology using a deep learning convolutional neural network (CNN). The apparatus includes a pre-processing circuit that generates a pre-processed WSI by downsampling a digital WSI. Additionally, an image acquisition circuit randomly selects a set of non-overlapping regions of interest (ROIs) from the pre-processed WSI and provides them to a deep learning circuit. The deep learning circuit generates an image-level probability that a member of the set of non-overlapping ROIs indicates failure or abnormal pathology. Finally, a classification circuit generates a patient-level probability that the patient from which the tissue region was acquired is experiencing failure or non-failure based on the image-level probability.
Career Highlights
Kenneth B. Margulies has established a notable career in the field of medical technology. He is currently affiliated with Case Western Reserve University, where he continues to advance research in cardiac health and technology. His innovative approach to utilizing deep learning in medical diagnostics sets him apart in his field.
Collaborations
Kenneth has collaborated with esteemed colleagues such as Anant Madabhushi and Jeffrey John Nirschl. Their combined expertise enhances the impact of their research and innovations in cardiac health.
Conclusion
Kenneth B. Margulies is a pioneering inventor whose work in predicting cardiac failure through advanced imaging techniques is making a significant difference in the medical field. His contributions are vital for improving patient outcomes and advancing healthcare technology.