Kenneth A Koeplinger

Title: Innovations of Kenneth A Koeplinger

Introduction

Kenneth A Koeplinger is a notable inventor based in Portage, MI (US). He has made significant contributions to the field of drug delivery and biochemistry, holding a total of 2 patents. His work focuses on innovative methods that enhance the efficacy of therapeutic agents.

Latest Patents

One of Koeplinger's latest patents is titled "Targeted drug delivery using sulfonamide derivatives." This invention relates to the use of Glutathione S-transferase (GST) and Reduced Glutathione (GSH) for the in-vivo release of drugs conjugated to specific electrophilic moieties via a sulfonamide bond. The drugs may include anticancer agents or other therapeutic properties, designed to be activated in the presence of specific targeting molecules. Another significant patent is the "Method for autoactivation of procaspase 8." This invention involves a novel recombinant procaspase 8 protein that lacks death effector domains, along with a method for converting this protein into fully active human caspase 8 through concentration on a collection device.

Career Highlights

Koeplinger has worked at Pharmacia & Upjohn Company, where he has been able to apply his innovative ideas in a practical setting. His contributions have been instrumental in advancing drug delivery systems and therapeutic methodologies.

Collaborations

Throughout his career, Koeplinger has collaborated with notable colleagues, including Alfredo Giuseppe Tomasselli and Tillie Peterson. These collaborations have further enriched his research and development efforts.

Conclusion

Kenneth A Koeplinger's work exemplifies the spirit of innovation in the pharmaceutical field. His patents reflect a commitment to improving drug delivery systems and therapeutic outcomes.