Kelvin Sham

Title: Kelvin Sham - Innovator in Metabolic Disorder Treatments

Introduction

Kelvin Sham is a notable inventor based in Thousand Oaks, CA (US). He has made significant contributions to the field of metabolic disorder treatments, particularly through his innovative patent.

Latest Patents

Kelvin Sham holds a patent titled "Method of treating or ameliorating metabolic disorders using GLP-1 receptor agonists conjugated to antagonists for gastric inhibitory peptide receptor (GIPR)." This patent provides methods for treating metabolic diseases and disorders using a composition that includes an antigen binding protein specific for the GIPR polypeptide conjugated to a GLP-1 receptor agonist. The patent addresses various metabolic diseases, including type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels, and diabetic nephropathy. In certain embodiments, the composition comprises an antibody or functional fragment that includes a cysteine at one or more conjugation sites, allowing for the GLP-1 receptor agonist to be conjugated through the side-chain of the cysteine residue.

Career Highlights

Kelvin Sham is currently employed at Amgen Inc., where he continues to work on innovative solutions for metabolic disorders. His expertise and dedication to research have positioned him as a valuable asset in the field.

Collaborations

Kelvin has collaborated with notable coworkers, including Yuan Cheng and Chawita Netirojjanakul, contributing to advancements in their shared research interests.

Conclusion

Kelvin Sham's work in developing treatments for metabolic disorders showcases his commitment to innovation and improving health outcomes. His patent reflects a significant step forward in addressing complex metabolic diseases.