Company Filing History:
Years Active: 2018-2025
Title: Kelli Bramlett: Innovator in Molecular Tagging and Gene Fusion Detection
Introduction
Kelli Bramlett is a prominent inventor based in Austin, TX (US). She has made significant contributions to the field of molecular biology, particularly in the areas of molecular tagging and gene fusion detection. With a total of 6 patents to her name, her work has advanced the understanding and application of genetic analysis.
Latest Patents
Kelli's latest patents include innovative methods, systems, compositions, kits, apparatus, and computer-readable media for molecular tagging. These inventions relate to a multiplex molecular tagging procedure that utilizes a variety of tags appended to polynucleotides. The unique characteristics of these tags allow for the identification and tracking of individual tagged molecules within a mixture. This technology is particularly useful for generating error-corrected sequencing data and detecting low-abundance target polynucleotides in nucleic acid samples.
Another notable patent involves methods for partner agnostic gene fusion detection. This method amplifies a nucleic acid sample using a primer pool to produce multiple amplicons corresponding to exon-exon junctions of a driver gene. The resulting amplicons are sequenced and analyzed to detect gene fusion events without prior knowledge of specific fusion partners or breakpoints.
Career Highlights
Kelli Bramlett is currently employed at Life Technologies Corporation, where she continues to innovate in the field of molecular biology. Her work has not only contributed to scientific advancements but has also paved the way for new diagnostic tools and methodologies in genetic research.
Collaborations
Throughout her career, Kelli has collaborated with notable colleagues, including Jian Gu and Dumitru Brinza. These partnerships have enhanced her research and contributed to the successful development of her patented technologies.
Conclusion
Kelli Bramlett's contributions to molecular tagging and gene fusion detection exemplify her innovative spirit and dedication to advancing genetic research. Her patents reflect a commitment to improving methodologies in the field, making her a significant figure in contemporary science.