Keld Sorensen

Title: Keld Sorensen: Innovator in Enzymatic Assays

Introduction

Keld Sorensen is a notable inventor based in Roscoe, Illinois, recognized for his contributions to the field of enzymatic assays. With a total of two patents to his name, Sorensen has made significant advancements in the measurement and purification of enzyme activity.

Latest Patents

Sorensen's latest patents include a method titled "Rapid assay for radioactive determination of protein kinase activity." This innovative approach improves existing methodologies by utilizing a membrane as the solid phase, allowing for efficient measurement of enzymatic activity through a rapid radioactive method. The process involves phosphorylating a peptide substrate and measuring the radioactivity of the phosphorylated peptide adsorbed to the membrane.

Another significant patent is the "Method for isolation and purification of enzyme-antibody conjugates." This process focuses on isolating an enzyme-antibody conjugate, specifically horseradish peroxidase or alkaline phosphatase, from an aqueous mixture. The method employs a water-insoluble stationary phase with chelated Ni²⁺ ions to bind the conjugate, followed by washing to remove unbound enzyme and eluting the conjugate in a purified form.

Career Highlights

Keld Sorensen is currently associated with Pierce Chemical Company, where he continues to innovate in the field of biochemical assays. His work has contributed to advancements in the efficiency and accuracy of enzyme activity measurements, which are crucial in various research and clinical applications.

Collaborations

One of Sorensen's notable collaborators is A Krishna Mallia, with whom he has worked on various projects related to enzymatic assays and purification techniques.

Conclusion

Keld Sorensen's contributions to the field of enzymatic assays through his innovative patents have significantly impacted biochemical research. His work continues to pave the way for advancements in the measurement and purification of enzyme activity.