This inventor holds 3 USPTO granted patents. Top assignees: Cancerforskningsfondet Af 1989, Fonden Til Fremme Af Eksperimental Cancerforskning, Fonden Til Fremme Af Eksperimentel Cancerforskning. Active years: 1995-2001.
Company Filing History:
Years Active: 1995-2001
Title: Keld Dano: Innovator in Cancer Research
Introduction
Keld Dano is a prominent inventor based in Charlottenlund, Denmark. He has made significant contributions to the field of cancer research, particularly through his innovative patents. With a total of 3 patents, Dano's work focuses on the development of monoclonal antibodies that have the potential to improve cancer diagnostics and treatment.
Latest Patents
Dano's latest patents include groundbreaking inventions such as the "PAI-1 determination and use thereof." This patent describes a monoclonal antibody that binds to human endothelial type plasminogen activator inhibitor (PAI-1), which is produced by dexamethasone-treated human HT-1080 fibrosarcoma cells. This antibody can be utilized to determine PAI-1 protein abundance in tumor tissues or body fluid samples. The measurements of this parameter may be instrumental in predicting tumor presence, metastasis, or the progression of known malignant tumors.
Another significant patent is related to "Urokinase-type plasminogen activator receptor antibodies." This invention involves monoclonal or polyclonal antibodies directed against the urokinase plasminogen activator receptor (u-PAR). These antibodies can react with free u-PAR or complexes between u-PA and u-PAR, enabling various applications such as ELISA detection, immunohistochemical detection in cancer cells, and inhibiting cell surface plasminogen activation.
Career Highlights
Throughout his career, Keld Dano has worked with notable organizations, including the Foundation for the Promotion of Experimental Cancer Research and the Cancer Research Fund of 1989. His work has significantly advanced the understanding of cancer biology and therapeutic approaches.
Collaborations
Dano has collaborated with esteemed colleagues such as Lars S. Nielsen and Gunilla Hoyer-Hansen. These partnerships have fostered innovation and contributed to the success of his research endeavors.
Conclusion
Keld Dano's contributions to cancer research through his innovative patents highlight his role as a leading inventor in the field. His work continues to pave the way for advancements in cancer diagnostics and treatment.