Keith Pardee

Title: Innovations of Keith Pardee

Introduction

Keith Pardee is a notable inventor based in Toronto, Canada. He has made significant contributions to the field of synthetic biology, particularly in the development of methods for detecting target analytes. With a total of four patents to his name, Pardee's work has the potential to impact various applications in healthcare and diagnostics.

Latest Patents

Pardee's latest patents include innovative methods for detecting target analytes using synthetic biological circuits that modify glucose levels in a cell-free system. These methods describe how to generate a reporter molecule in response to a target analyte, utilizing a synthetic biological circuit to adjust the level of the reporter molecule based on the presence of the target analyte. The reporter molecule can be glucose or another detectable molecule, which can be monitored using devices like glucose monitors or portable sensors. Another significant patent focuses on a portable, low-cost pathogen detection and strain identification platform. This patent outlines methods for detecting pathogen-specific RNA in biological samples, employing toehold switch sensors and isothermal amplification to identify target nucleic acids, including viruses like the Zika virus.

Career Highlights

Throughout his career, Keith Pardee has worked with prestigious institutions such as Arizona State University and the Massachusetts Institute of Technology. His research has been pivotal in advancing the field of synthetic biology and diagnostics.

Collaborations

Pardee has collaborated with notable individuals in his field, including Alexander A Green and Dana Braff. These collaborations have contributed to the development of his innovative patents and research.

Conclusion

Keith Pardee's contributions to synthetic biology and diagnostics through his patents demonstrate his commitment to innovation in healthcare. His work continues to pave the way for advancements in pathogen detection and analysis.