Keith A Knisley

Title: Keith A. Knisley: Innovator in Ampholyte Analysis

Introduction: Keith A. Knisley is a prominent inventor based in Lubbock, Texas, with a keen focus on the synthesis and analysis of novel ampholytes. His significant contributions to the field have culminated in a unique patent that enhances the understanding and application of ampholytes in various scientific processes.

Latest Patents: Knisley holds a patent titled "Analysis of Carrier Ampholytes Using Immobilized pH Gradients - New Synthesis and Analysis Procedures for Novel Crosslinked Polyamines and Ampholytes." This innovative patent introduces a process where polyamines are crosslinked with compounds such as tartaric acid ester and malonic acid ester. The resultant crosslinked polyamines can react with .alpha., .beta.-unsaturated or .alpha.-halo unsaturated carboxylic acids, yielding new ampholyte mixtures characterized by increased heterogeneity and complexity compared to currently available ampholytes. These novel ampholytes have significant applications in analytical and preparative isoelectric focusing processes.

Career Highlights: Knisley is associated with the University of Texas System, where he conducts research and develops methodologies aimed at enhancing biochemical analyses. His work not only contributes to academic knowledge but also has practical implications in various scientific fields.

Collaborations: He frequently collaborates with L. Scott Rodkey, working together to explore and innovate in the realm of ampholyte analysis. Their joint efforts have played a crucial role in advancing techniques that benefit analytical chemistry.

Conclusion: Keith A. Knisley's contributions to the field of ampholytes through his patent and research at the University of Texas System underscore the importance of innovation in scientific inquiry. His work exemplifies how inventive approaches can lead to significant advancements in both academic and practical applications within biochemistry.