Company Filing History:
Years Active: 2009-2012
Title: Keiko Kadono: Pioneering Insect Desiccation Resistance Research
Introduction
Keiko Kadono is an innovative inventor based in Tsukuba, Japan. She has made significant contributions to the field of biotechnology, particularly in the area of insect desiccation resistance. With a total of 3 patents to her name, her work has implications for agricultural science and pest management.
Latest Patents
One of her latest patents focuses on insect desiccation resistance genes and their applications. The objective of this invention is to provide polynucleotides encoding insect desiccation resistance proteins. cDNA libraries were produced from larvae in a desiccated state, leading to the construction of an EST database and the isolation of genes encoding LEA proteins. This research resulted in the successful isolation of three novel genes encoding LEA-like proteins, namely PvLEA1, PvLEA2, and PvLEA3.
When secondary structure predictions and motif searches were conducted on the proteins derived from these genes, all three proteins exhibited α-helix-rich structures and LEA_4 motifs, which are characteristic of LEA proteins. Furthermore, the recombinant proteins synthesized from these genes were found to be heat soluble, even at boiling temperatures, indicating their highly hydrophilic properties similar to plant LEA proteins. The introduction of these genes into animal cells successfully conferred desiccation resistance to the cells, marking a significant advancement in the field.
Career Highlights
Keiko Kadono is affiliated with the National Institute of Agrobiological Sciences, where she conducts her research. Her work has garnered attention for its innovative approach to understanding and enhancing desiccation resistance in insects.
Collaborations
Some of her notable coworkers include Takahiro Kikawada and Takashi Okuda, who have collaborated with her on various research projects.
Conclusion
Keiko Kadono's contributions to the field of insect desiccation resistance are noteworthy and have the potential to impact agricultural practices significantly. Her innovative research continues to pave the way for advancements in biotechnology.
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