Company Filing History:
11 out of 504 
1 out of 48 
1 out of 832,880 Years Active: 1995-2006
Title: The Innovative Contributions of Ke-fei Shen
Introduction
Ke-fei Shen is a prominent inventor based in Flushing, NY, known for his significant contributions to the field of analgesic research. With a total of 13 patents to his name, Shen has focused on developing methods to enhance the efficacy of opioid medications while minimizing their adverse effects. His work is particularly relevant in the context of the ongoing opioid crisis, as it seeks to improve pain management strategies.
Latest Patents
One of Shen's latest patents is titled "Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists." This invention outlines a method for selectively enhancing the analgesic potency of bimodally-acting opioid agonists, such as morphine, while simultaneously reducing the negative effects associated with their use. The method involves administering an analgesic amount of the opioid agonist along with an excitatory opioid receptor antagonist, such as naltrexone or nalmefene, to achieve these dual benefits.
Another notable patent is "Compositions and methods for enhancing analgesic potency of tramadol and attenuating its adverse side effects." This invention focuses on the use of tramadol in combination with an opioid antagonist to enhance its analgesic effects and reduce adverse side effects, including nausea, dizziness, and sedation. The approach aims to improve patient outcomes by addressing the challenges associated with tramadol use.
Career Highlights
Throughout his career, Ke-fei Shen has worked with esteemed organizations, including Albert Einstein College of Medicine and United Biomedical, Inc. His research has contributed to advancements in pain management and has garnered attention for its innovative approach to opioid use.
Collaborations
Shen has collaborated with notable colleagues, including Stanley M Crain and Gerald M Fleischner, further enriching his research and development efforts in the field of analgesics.
Conclusion
Ke-fei Shen's innovative work in enhancing the efficacy of opioid medications while mitigating their adverse effects positions him as a key figure in the ongoing efforts to improve pain management. His contributions are vital in addressing the complexities of opioid use in clinical settings.