This inventor holds 1 USPTO granted patent. Top assignee: Mitsui Toatsu Chemicals, Incorporated. Active years: 1992.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1992
Title: Innovator Kazunori Ando: A Pioneer in Thrombin Inhibition
Introduction: Kazunori Ando, based in Mobara, Japan, is an esteemed inventor recognized for his significant contributions in the field of biotechnology. He has developed a unique polypeptide demonstrating thrombin inhibiting activity, showcasing his expertise in molecular biology and innovative therapeutic solutions.
Latest Patents: Kazunori Ando holds one patent titled "Polypeptide having thrombin inhibiting activity." This patent describes a modified HV1-type hirudin, where valine at the N-terminal end has been replaced with alanine and aspartic acid at the 5th residue of the N-terminal end has been substituted with glutamic acid. The invention further includes a secretion plasmid integrating a DNA sequence coding for a precursor with an added secretion signal of neutral protease from Bacillus amyloliquefaciens at the N-terminal end. This enables the precursor to be expressed intracellularly in Bacillus bacteria, allowing for efficient extracellular secretion of the modified HV1-type hirudin, maintaining its high thrombin inhibiting efficacy.
Career Highlights: Kazunori Ando works at Mitsui Toatsu Chemicals, Incorporated, where he has been instrumental in advancing biotechnological applications. His innovative approach and keen understanding of protein modifications have positioned him as a key figure in the development of therapeutic agents targeting thrombin.
Collaborations: Throughout his career, Ando has collaborated with talented colleagues such as Yoshio Furutani and Masaru Honjo. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and in-depth research, further enhancing the impact of their work in the biochemistry field.
Conclusion: Kazunori Ando's inventive contributions, particularly in the realm of thrombin inhibition, underscore the importance of innovation within biotechnology. His patent and collaborative efforts exemplify the progressive strides being made in medical science and offer promising avenues for future research and therapeutic developments.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile