This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignees: Harvard College, Sankyo Company, Limited. Active years: 2009-2019.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2009-2019
Title: Kazuishi Kubota: Innovator in Kinase Activity Screening
Introduction
Kazuishi Kubota is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the field of biotechnology, particularly in the area of kinase activity screening. With a total of 2 patents, his work has paved the way for advancements in diagnostic methods and therapeutic agent discovery.
Latest Patents
One of Kubota's latest patents focuses on methods, compositions, and kits for high throughput kinase activity screening using mass spectrometry and stable isotopes. This innovative mass-spectrometry-based method allows for large-scale kinome activity profiling directly from crude lysates. It utilizes 90 chemically synthesized peptide substrates derived from known phosphoproteins. The quantification of peptide phosphorylation rates is achieved through stable isotope labeled synthetic peptides. This method enables the simultaneous measurement of multiple peptide phosphorylation rates, providing a diagnostic fingerprint pattern for activated kinases and pathways from minimal starting material.
Another notable patent involves 2',5'-oligoadenylate phosphodiesterase. This invention includes polypeptides with 2',5'-oligoadenylate phosphodiesterase activity, antibodies against these polypeptides, and processes for screening inhibitors of this enzyme. The polypeptides and host cells developed through this research are valuable for identifying therapeutic agents for viral infections and tumors.
Career Highlights
Kazuishi Kubota has worked with prestigious institutions, including Harvard College and Sankyo Company, Limited. His experience in these organizations has contributed to his expertise in the field of biotechnology and patent development.
Collaborations
Throughout his career, Kubota has collaborated with notable individuals such as Steven P. Gygi and Judit Villen. These partnerships have further enhanced his research and innovation capabilities.
Conclusion
Kazuishi Kubota's contributions to kinase activity screening and therapeutic agent discovery highlight his role as a leading inventor in biotechnology. His innovative patents and collaborations continue to influence the field and pave the way for future advancements.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile