Kaustabh Basu

Title: Innovations of Kaustabh Basu in PI4-Kinase Inhibitors

Introduction

Kaustabh Basu is an accomplished inventor based in Redwood City, CA. He has made significant contributions to the field of biochemistry, particularly in the development of PI4-kinase inhibitors. His work focuses on creating compounds that can effectively inhibit PI4-kinase, which has implications for treating various diseases, including cancer and pathogen infections.

Latest Patents

Kaustabh Basu holds a patent for "PI4-kinase inhibitors and methods of using the same." This patent describes compounds and methods for inhibiting PI4-kinase, which is crucial for treating infections caused by pathogens and for cancer therapy. The patent outlines that the PI4-kinase inhibitor can be a compound such as a 5-aryl or heteroaryl-thiazole. In particular, it includes substituted 2-amino-5-phenylthiazole or substituted 2-amino-5-pyridylthiazole compounds. These compounds exhibit broad-spectrum anti-infective activity against various diseases caused by pathogens that interact with phosphatidylinositol 4,5-bisphosphate (PIP-2) to facilitate replication. Additionally, the methods provided in the patent include inhibiting PI4-kinase in cancer cells to reduce cellular proliferation.

Career Highlights

Kaustabh Basu is affiliated with Leland Stanford Junior University, where he continues to advance his research in the field of biochemistry. His innovative work has garnered attention for its potential applications in medical treatments.

Collaborations

Kaustabh has collaborated with notable colleagues such as Jeffrey S. Glenn and Mark Smith, contributing to the advancement of research in his field.

Conclusion

Kaustabh Basu's contributions to the development of PI4-kinase inhibitors represent a significant advancement in the fight against cancer and infectious diseases. His innovative research continues to pave the way for new therapeutic methods.