Location History:
- Agoura, CA (US) (1998)
- Oak Park, CA (US) (2013 - 2018)
- Canoga Park, CA (US) (2023)
Company Filing History:
Years Active: 1998-2023
Title: Innovations by Katsuyuki Saito
Introduction
Katsuyuki Saito is a notable inventor based in Oak Park, California. He has made significant contributions to the field of biotechnology, particularly in the area of genetic testing. With a total of 4 patents to his name, Saito's work has advanced the methods used for HLA typing and nucleic acid detection.
Latest Patents
One of Saito's latest patents is a method for single reaction multiplex PCR primer design aimed at amplifying multiple HLA class I and II genes. This innovative approach provides next-generation sequencing (NGS)-based high-resolution HLA typing as a routine clinical test. The method simplifies the protocol for typing multiple HLA genes by reducing the number of amplification reactions nearly ten-fold, resulting in a substantially equimolar ratio of individual HLA gene amplification products. This invention also eliminates the need for an amplicon pooling step, which reduces both reagent costs and the required sample DNA quantity.
Another significant patent by Saito is a diagnostic probe detection system. This invention offers methods for detecting target nucleic acid sequences using diagnostic probes that include first and second probe regions. These regions are substantially complementary to first and second target regions on a target nucleic acid strand. The design ensures that when the first target region is contiguous with the second target region, the probe regions are separated by a spacer region of nucleic acid, enhancing the detection process.
Career Highlights
Katsuyuki Saito is currently employed at One Lambda, Inc., where he continues to innovate in the field of genetic testing. His work has been instrumental in developing more efficient and cost-effective methods for HLA typing and nucleic acid detection.
Collaborations
Saito has collaborated with notable colleagues such as Jar-How Lee and Lindley Blair, contributing to advancements in their shared field of expertise.
Conclusion
Katsuyuki Saito's contributions to biotechnology through his patents have significantly improved the efficiency of genetic testing methods. His innovative approaches continue to influence the field and enhance clinical practices.