Company Filing History:
Years Active: 2015-2017
Title: Katrin Tiemann: A Pioneer in RNA Aptamer Technology
Introduction
Katrin Tiemann, a pioneering inventor based in Pasadena, CA, has made significant contributions to the field of biotechnology. With three patents to her name, she focuses on the development of RNA aptamers that hold promise for targeted cancer therapies.
Latest Patents
Among her latest inventions is the innovative patent titled "RNA aptamers against BAFF-R as cell-type specific delivery agents and methods for their use." This patent introduces a B cell specific aptamer-siRNA chimera designed to bind to BAFF-R, coupled with an siRNA molecule through a nucleotide linker. The invention potentially allows for the targeted suppression of oncogenes such as Bcl6, Bcl2, STAT3, Cyclin D1, Cyclin E2, and c-myc in B cells. Additionally, the patent outlines methods for treating B cell malignancies in cancer patients by administering a therapeutically effective composition containing these specific RNA aptamers.
Career Highlights
Katrin Tiemann has established a noteworthy career at City of Hope, where she engages in cutting-edge research to advance cancer treatment methodologies. Her work revolves around harnessing RNA aptamers as innovative cell-type specific delivery agents that can revolutionize therapeutic approaches for patients suffering from B cell malignancies.
Collaborations
Throughout her career, Tiemann has collaborated with esteemed colleagues such as John J Rossi and Jiehua Zhou. Their joint efforts in the field of biotechnology exemplify the collaborative spirit present in research institutions focused on transformative health solutions.
Conclusion
Katrin Tiemann stands out as an influential figure in the realm of biotechnological innovations, particularly for her development of RNA aptamers targeting BAFF-R. Her contributions not only enhance the scientific community’s understanding of cancer therapies but also pave the way for future advancements in targeted treatment strategies. With her ongoing work at City of Hope and collaborative efforts, Tiemann continues to inspire and drive innovation in the field.