Company Filing History:
Years Active: 2016-2025
Title: Innovations in HIV Treatment by Katherine Doores
Introduction
Katherine Doores is a prominent inventor based in San Diego, CA, known for her significant contributions to the field of HIV research. With a total of six patents to her name, she has made remarkable strides in developing methods for treating HIV-1 infections.
Latest Patents
Her latest patents focus on methods of treating HIV-1 infection utilizing broadly neutralizing human immunodeficiency virus type 1 (HIV-1) GP120-specific monoclonal antibodies. The invention outlines a method for obtaining a broadly neutralizing antibody (bNab) by screening memory B cell cultures from a donor PBMC sample for neutralization activity against various HIV-1 species. It includes cloning a memory B cell that exhibits broad neutralization activity and rescuing a monoclonal antibody from that culture. The resultant monoclonal antibodies are characterized by their ability to selectively bind epitopes from the Env proteins in both native and monomeric forms, as well as to inhibit infection from multiple HIV-1 clades. Additionally, the patents provide compositions containing human monoclonal anti-HIV antibodies for prophylaxis, diagnosis, and treatment of HIV infection. Methods for generating such antibodies through immunization using epitopes from conserved regions within the variable loops of gp120 are also included.
Career Highlights
Katherine has worked with notable organizations such as Theraclone Sciences, Inc. and The Scripps Research Institute. Her work has been instrumental in advancing the understanding and treatment of HIV, showcasing her dedication to improving public health.
Collaborations
Some of her notable coworkers include Po-Ying Chan-Hui and Michael Huber, who have collaborated with her on various research projects.
Conclusion
Katherine Doores continues to be a leading figure in HIV research, with her innovative patents paving the way for new treatment methods. Her contributions are vital in the ongoing fight against HIV, and her work exemplifies the impact of dedicated inventors in the field of medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.