San Diego, CA, United States of America

Katherine Doores

USPTO Granted Patents = 6 

Average Co-Inventor Count = 14.0

ph-index = 2

Forward Citations = 27(Granted Patents)


Company Filing History:


Years Active: 2016-2025

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6 patents (USPTO):Explore Patents

Title: Innovations in HIV Treatment by Katherine Doores

Introduction

Katherine Doores is a prominent inventor based in San Diego, CA, known for her significant contributions to the field of HIV research. With a total of six patents to her name, she has made remarkable strides in developing methods for treating HIV-1 infections.

Latest Patents

Her latest patents focus on methods of treating HIV-1 infection utilizing broadly neutralizing human immunodeficiency virus type 1 (HIV-1) GP120-specific monoclonal antibodies. The invention outlines a method for obtaining a broadly neutralizing antibody (bNab) by screening memory B cell cultures from a donor PBMC sample for neutralization activity against various HIV-1 species. It includes cloning a memory B cell that exhibits broad neutralization activity and rescuing a monoclonal antibody from that culture. The resultant monoclonal antibodies are characterized by their ability to selectively bind epitopes from the Env proteins in both native and monomeric forms, as well as to inhibit infection from multiple HIV-1 clades. Additionally, the patents provide compositions containing human monoclonal anti-HIV antibodies for prophylaxis, diagnosis, and treatment of HIV infection. Methods for generating such antibodies through immunization using epitopes from conserved regions within the variable loops of gp120 are also included.

Career Highlights

Katherine has worked with notable organizations such as Theraclone Sciences, Inc. and The Scripps Research Institute. Her work has been instrumental in advancing the understanding and treatment of HIV, showcasing her dedication to improving public health.

Collaborations

Some of her notable coworkers include Po-Ying Chan-Hui and Michael Huber, who have collaborated with her on various research projects.

Conclusion

Katherine Doores continues to be a leading figure in HIV research, with her innovative patents paving the way for new treatment methods. Her contributions are vital in the ongoing fight against HIV, and her work exemplifies the impact of dedicated inventors in the field of medicine.

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