Kasper Philipp Holliger

Title: Kasper Philipp Holliger: Innovator in Specific Binding Pairs

Introduction

Kasper Philipp Holliger is a notable inventor based in Cambridge, GB. He has made significant contributions to the field of biotechnology, particularly in the development of methods for producing members of specific binding pairs. His innovative approach has implications for various applications, including antibody development.

Latest Patents

Holliger holds a patent titled "Methods for producing members of specific binding pairs." This patent describes a method for identifying members of specific binding pairs by expressing DNA encoding a genetically diverse population of such members in recombinant host cells. The members are displayed in functional form at the surface of a secreted recombinant genetic display package. This method allows for the selection of displayed specific binding pairs through affinity with complementary members, leading to the recovery of DNA for further expression. The use of a phagemid as an expression vector enhances the packaging of the phagemid DNA, enabling the creation of libraries with greater genetic diversity than conventional methods.

Career Highlights

Throughout his career, Holliger has worked with esteemed organizations such as the Medical Research Council and MedImmune Limited. His work in these institutions has contributed to advancements in medical research and biotechnology.

Collaborations

Holliger has collaborated with notable individuals in his field, including John Gerald McCafferty and Anthony Richard Pope. These collaborations have further enriched his research and innovations.

Conclusion

Kasper Philipp Holliger's contributions to the field of biotechnology, particularly through his patent on specific binding pairs, highlight his role as an influential inventor. His work continues to impact the development of innovative solutions in medical research.