Location History:
- Oakland, CA (US) (1986)
- Kensington, CA (US) (1986 - 1997)
- La Jolla, CA (US) (1989 - 2003)
Company Filing History:
10 out of 212 
5 out of 4,942 
3 out of 621 
Years Active: 1986-2003
Title: Kary B Mullis: Pioneer in Nucleic Acid Amplification
Introduction:
Kary B Mullis, a renowned scientist and inventor, made significant contributions to the field of molecular biology with his groundbreaking invention of the polymerase chain reaction (PCR). Born on December 28, 1944, in Lenoir, North Carolina, Mullis obtained his Bachelor of Science degree in Chemistry from the Georgia Institute of Technology in 1966. Throughout his career, he held positions in esteemed companies such as Cetus Corporation and Hoffmann-La Roche Inc. This article explores Mullis' latest patents, career highlights, and notable collaborations.
Latest Patents:
One of Mullis' most significant inventions is the process for amplifying and detecting nucleic acid sequences using a thermostable enzyme. This invention is carried out through the polymerase chain reaction (PCR) methodology. The PCR enables the amplification of any target nucleic acid sequence, allowing for the detection and analysis of genetic material. This breakthrough technology revolutionized molecular biology, cloning, forensics, medical diagnostics, and various other fields.
Career Highlights:
Mullis' career highlights include his time at Cetus Corporation, where he conducted the crucial research behind the development of PCR. He later joined Hoffmann-La Roche Inc., further advancing PCR technology and collaborating with scientists to explore its various applications.
Collaborations:
During his career, Mullis collaborated with several notable scientists, contributing to the advancement of PCR technology. One of his key collaborations was with Henry A. Erlich, a researcher at Cetus Corporation. Together, they refined the PCR technique and expanded its potential applications, such as DNA fingerprinting and DNA sequencing. Another significant collaboration was with Randall K. Saiki, who worked alongside Mullis at Cetus Corporation, contributing to the optimization and improvement of PCR protocols.
Conclusion:
Kary B Mullis played a vital role in revolutionizing the field of molecular biology through his invention of the polymerase chain reaction (PCR). His innovative work has had a profound impact on various scientific disciplines, enabling advancements in genetic research, diagnostics, medicine, and forensic science. Mullis' patents and collaborations solidify his significant contributions to the scientific community, and his work continues to shape the landscape of molecular biology to this day.
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