Karsten Mader

Title: The Innovative Contributions of Karsten Mader

Introduction

Karsten Mader is a notable inventor based in White River Junction, VT (US). He has made significant contributions to the field of biological measurement through his innovative patent. His work focuses on the measurement of oxygen tensions in biological systems, which is crucial for various medical and research applications.

Latest Patents

Karsten Mader holds a patent for an "Apparatus and methodology for determining oxygen tension in biological systems." This invention provides apparatus and methods for measuring oxygen tensions in biological systems utilizing physiologically acceptable paramagnetic material, such as India ink or carbon black, and electron paramagnetic resonance (EPR) oximetry. The invention introduces India ink to the biological system, which is then exposed to a magnetic field and an electromagnetic field in the 1-2 GHz range. The EPR spectra is measured at the biological system to determine oxygen concentration. The EPR spectra is determined by an EPR spectrometer that adjusts the resonator to a single resonator frequency to compensate for movements of the biological system, such as a human or animal. The biological system can also include other in vivo tissues, cells, and cell cultures to directly measure pO2 non-destructively. The paramagnetic material can be used non-invasively or invasively depending on the goals of the pO2 measurement. A detecting inductive element, as part of the EPR spectrometer resonator, is adapted relative to the measurement particularities. Mader's innovative approach has led to the development of a method that enhances the accuracy and efficiency of oxygen measurement in biological contexts.

Career Highlights

Karsten Mader is affiliated with Dartmouth College, where he continues to contribute to research and innovation in the field of biological measurement. His work has garnered attention for its potential applications in medical diagnostics and research.

Collaborations

Mader has collaborated with notable colleagues, including Tadeusz Walczak and Fuminori Goda. These collaborations have further enriched his research and contributed to advancements in the field.

Conclusion

Karsten Mader's innovative work in measuring oxygen tensions in biological systems exemplifies the importance of invention in advancing medical technology. His contributions are significant in enhancing our understanding of biological processes and improving diagnostic methods.