Location History:
- Binningen, CH (1977)
- Oberwil, CH (1981 - 1985)
Company Filing History:
Years Active: 1977-1985
Title: Karl Schaffner: A Pioneer in Pharmaceutical Innovations
Introduction: Karl Schaffner, an influential inventor based in Oberwil, Switzerland, has made significant contributions to the field of pharmaceuticals with a focus on antimicrobial compounds. With a total of three patents to his name, Schaffner's innovative approaches have advanced the development of essential antibiotics.
Latest Patents: Among Karl Schaffner's most notable achievements is his recent patent for 6-Azaoligocycloalkylmethyleneaminopenam compounds. This invention relates to 6-amino-penam compounds exhibiting antimicrobial action. The unique formula outlines a complex structure where R1 represents an azaoligocycloalkyl radical, featuring at least one endo-bridge atom and a total of 7 to 12 ring atoms. Furthermore, his research delves into processes for the preparation of pharmaceutical formulations containing these compounds. These preparations aim to combat various microorganisms, improving treatment efficacy against infections.
Another recent patent involves a fragmentation procedure for preparing 3-amino-azetidinones. The method details how 3-(2-hydroxyiminoacetylamino)-2-oxo-azetidine compounds, when treated with reactive derivatives of carbonic acid half-esters in aqueous media, yield valuable intermediates for nocardicin-like antibiotics. This innovative approach enhances the yield of 3-amino-2-oxo-azetidine compounds while simplifying the deacylation process.
Career Highlights: Karl Schaffner has established himself as a key inventor at Ciba-Geigy Corporation, a respected name in the pharmaceutical industry. His work has significantly impacted the development of antibiotic compounds, making strides in the battle against resistant infections. Schaffner's inventive skills and dedication to pharmaceutical science have earned him recognition in his field.
Collaborations: Throughout his career, Karl Schaffner has collaborated with notable colleagues, including Riccardo Scartazzini and Hansuli Wehrli. Their joint efforts have contributed to the successful development of innovative pharmaceutical solutions, underscoring the importance of teamwork in scientific research.
Conclusion: Karl Schaffner stands out as a prominent figure in the realm of pharmaceutical innovation. With his noteworthy patents and collaborative efforts, he has made lasting contributions that continue to influence antimicrobial research and the fight against infectious diseases. His work exemplifies the significance of innovation in enhancing public health and developing effective medical remedies.