Karl-Peter Hopfner

Title: The Innovations of Karl-Peter Hopfner

Introduction

Karl-Peter Hopfner is a notable inventor based in Munich, Germany. He has made significant contributions to the field of protease research, holding a total of 4 patents. His work focuses on the development of innovative proteases that have applications in various biomedical fields.

Latest Patents

One of his latest patents is for chimeric serine proteases. This invention describes a chimeric serine protease whose protease domain is composed of two domain halves with a β-folded sheet structure. The first domain half corresponds to the first domain half of a first serine protease, while the second domain half corresponds to the second domain half of a second serine protease. This design results in improved properties and allows for easy crystallization. Another significant patent involves recombinant blood-coagulation proteases. This invention relates to a non-glycosylated protein with enzymatic and serine protease activity. The zymogenous form comprises a catalytic domain, a zymogenous activation domain, and an EGF1 and/or EGF2 domain. This protein can be utilized similarly to the natural serine proteases of the factor IX family.

Career Highlights

Throughout his career, Karl-Peter Hopfner has worked with prominent companies such as Boehringer Mannheim GmbH and Roche Diagnostics GmbH. His experience in these organizations has contributed to his expertise in the field of protease research and development.

Collaborations

He has collaborated with notable colleagues, including Erhard Kopetzki and Wolfram Bode. These partnerships have further enhanced his research and innovation capabilities.

Conclusion

Karl-Peter Hopfner's contributions to the field of protease research are significant and impactful. His innovative patents and collaborations reflect his dedication to advancing biomedical science.