Company Filing History:
Years Active: 1979-1987
Title: Innovations of Karl J Sanford
Introduction
Karl J Sanford is a notable inventor based in Rochester, NY (US). He has made significant contributions to the field of immunoassays and has been awarded a total of 7 patents. His work has advanced the methods used for determining various ligands in liquid samples.
Latest Patents
Among his latest patents is a heterogeneous immunoassay utilizing horizontal separation. This innovative method involves conducting a competitive binding immunoassay with a dry analytical element. The process is designed to determine a ligand, such as a therapeutic drug, by contacting a finite area of the element's spreading layer with a liquid sample. This method allows for the formation of an immobilized ligand-receptor complex while simultaneously enabling the uncomplexed ligand to migrate horizontally away from the complex. The amount of immobilized complex is measured after a brief period, enhancing the accuracy of the assay.
Another significant patent is the method and element for albumin assay. This assay utilizes a specific dye that exhibits a high affinity for albumin across a wide pH range. When the dye binds to albumin, a spectral absorption shift occurs, allowing for precise determination of albumin levels in liquid samples. The analytical elements containing this dye and the corresponding assay method represent a substantial advancement in the field.
Career Highlights
Karl J Sanford has spent a considerable part of his career at Eastman Kodak Company, where he has been able to apply his innovative ideas and research. His work has not only contributed to the company's portfolio but has also had a lasting impact on the industry.
Collaborations
Throughout his career, Sanford has collaborated with notable colleagues, including Jon N Eikenberry and Paul H Frickey. These collaborations have fostered an environment of innovation and have led to the development of groundbreaking technologies.
Conclusion
Karl J Sanford's contributions to the field of immunoassays and his innovative patents highlight his role as a significant inventor. His work continues to influence the industry and improve methods for analyzing liquid samples.
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