Location History:
- Wiilow Grove, PA (US) (1998)
- Hatboro, PA (US) (2008 - 2014)
- Waunakee, WI (US) (2015)
- Willow Grove, PA (US) (1999 - 2019)
Company Filing History:
7 out of 50 
2 out of 9 
2 out of 1,777 
Years Active: 1998-2019
Title: The Innovative Mind of Inventor Karl Frank Johnson
Introduction: Karl Frank Johnson, an accomplished inventor based in Hatboro, PA, has made significant contributions to the field of enzymology with his 14 patents. His work focuses on enhancing synthetic activities of enzymes, particularly in the synthesis of complex molecules like glycolipids.
Latest Patents: Among his latest innovations is the patent for "Mutant endoglycoceramidases with enhanced synthetic activity." This invention pertains to a novel endoglycoceramidase whose hydrolytic activity has been either substantially reduced or eliminated. Johnson's innovative enzyme facilitates the synthesis of glycolipids from monosaccharides or oligosaccharides and ceramides. More specifically, this mutant enzyme features mutations within its active site or nucleophilic site, including a noteworthy substitution of the Glu residue. The patent also describes methods for generating the mutant enzyme and ways to utilize it enzymatically to synthesize glycolipids.
Career Highlights: Karl Frank Johnson has been recognized in the industry for his pioneering work in developing enzymes that not only simplify but also enhance the efficiency of biochemical synthesis. His expertise has led to advancements that are vital for various applications, particularly in biotechnology and pharmaceuticals.
Collaborations: Throughout his career, Johnson has collaborated with notable professionals, including Shawn DeFrees and Daniel James Bezila. Additionally, he has held positions at reputable companies such as Neose Technologies, Inc. and Biogenerix AG, contributing his innovative spirit to teams dedicated to research and development in biochemistry.
Conclusion: Karl Frank Johnson stands out as a distinguished inventor whose breakthroughs in enzyme technology have significant implications for biochemical research and application. His dedication to innovation continues to leave a lasting impact in the scientific community, further establishing him as a prominent figure in the field of enzymatic synthesis.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.