This inventor holds 1 USPTO granted patent. Top assignee: Harvard College. Active years: 2001.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2001
Title: Karl E. Klose: Inventor in Attenuated Microorganism Technology
Introduction
Karl E. Klose is an inventor associated with Newton, Massachusetts, and Harvard College. His patent work concerns attenuated microorganisms and a method for preparing a live, non-virulent vaccine.
Latest Patents
Klose is credited with 1 patent: “Attenuated Auxotrophic Microorganisms Having a Combination of Non-Attenuating Mutations and Method for Making Same.” The patent describes a vaccine composition and preparation method involving a microorganism with at least two mutations. One mutation creates an auxotrophic strain that requires a nutrient for proliferation. The other prevents the strain from specifically transporting that nutrient from host tissues, resulting in an attenuated microorganism.
Career Highlights
Klose’s listed invention addresses a strategy for attenuating microorganisms through a combination of mutations. The patent describes how this approach may be used in preparing a live, non-virulent vaccine.
Collaborations
Klose’s listed coworker is John J. Mekalanos. Their association is connected with the patent on attenuated auxotrophic microorganisms and vaccine preparation.
Conclusion
Karl E. Klose’s patent reflects work on combining microbial mutations to produce attenuated strains for vaccine applications.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile