Karin Lehmann-Bruinsma

Title: The Innovative Contributions of Karin Lehmann-Bruinsma

Introduction

Karin Lehmann-Bruinsma is a prominent inventor based in San Diego, CA. She has made significant contributions to the field of biotechnology, particularly in the area of G protein-coupled receptors (GPCRs). With a total of 3 patents to her name, her work has advanced the understanding and application of these important receptors in drug discovery.

Latest Patents

One of her latest patents focuses on "Non-endogenous, constitutively activated known G protein-coupled receptors." This invention relates to transmembrane receptors, specifically human GPCRs for which the endogenous ligand is known. The patent details mutated (non-endogenous) versions of these known GPCRs, which are intended for use in screening assays. These assays aim to directly identify candidate compounds as inverse agonists, agonists, and partial agonists.

Career Highlights

Karin is currently associated with Arena Pharmaceuticals, Inc., where she continues to innovate and contribute to the field. Her expertise in GPCRs has positioned her as a key figure in the development of new therapeutic strategies.

Collaborations

Throughout her career, Karin has collaborated with notable colleagues, including Chen Wang Liaw and I-Lin Lin. These partnerships have further enhanced her research and the impact of her inventions.

Conclusion

Karin Lehmann-Bruinsma's work exemplifies the spirit of innovation in biotechnology. Her contributions to the understanding of GPCRs are paving the way for new advancements in drug discovery and therapeutic applications.