Company Filing History:
Years Active: 2000
Title: The Innovations of Karin K Hale
Introduction
Karin K Hale is a notable inventor based in Boulder, CO (US). She has made significant contributions to the field of biotechnology, particularly in the development of tumor necrosis factor (TNF) inhibitors. Her work has implications for treating various diseases, showcasing her innovative spirit and dedication to scientific advancement.
Latest Patents
Karin K Hale holds a patent for a "Tumor necrosis factor (TNF) inhibitor and method for obtaining the same." This patent discloses at least two substantially purified TNF inhibitors, which are glycoproteins active against TNF. The isolation of 30 kDa and 40 kDa TNF inhibitors from urine is detailed in her patent. The deglycosylated forms of these inhibitors are described as being active against TNF. Notably, the 40 kDa TNF inhibitor is effective against both TNF alpha and TNF beta. The patent also includes the amino acid sequences of the 30 kDa and 40 kDa TNF inhibitors, along with methods for isolating these inhibitors from human U937 cell medium and producing the proteins through recombinant-DNA methods.
Career Highlights
Karin K Hale is associated with Amgen Inc., a leading biotechnology company known for its innovative therapies. Her work at Amgen has allowed her to contribute to groundbreaking research and development in the field of medicine.
Collaborations
Karin has collaborated with notable colleagues, including Michael T Brewer and Michael W King. These partnerships have further enhanced her research and innovation efforts.
Conclusion
Karin K Hale's contributions to the field of biotechnology, particularly through her patent on TNF inhibitors, highlight her role as an influential inventor. Her work continues to pave the way for advancements in medical treatments.