Company Filing History:
4 out of 20 
1 out of 3 Years Active: 2015-2019
Title: The Innovative Contributions of Karin Henderika Maria Bessembinder
Introduction
Karin Henderika Maria Bessembinder is a notable inventor based in Echt, Netherlands. She has made significant contributions to the field of pharmaceuticals, particularly in the development of statin precursors and HMG-CoA reductase inhibitors. With a total of five patents to her name, Bessembinder's work has had a considerable impact on the pharmaceutical industry.
Latest Patents
One of her latest patents is a process for preparing a statin precursor. This invention involves a multi-step reaction process that includes the reaction of a hydroxy-pyrimidine-carbonitrile with an organic sulfonyl halide to form a sulfonate-pyrimidine-carbonitrile. The subsequent steps involve the formation of a pyrimidinyl-sulfonamide and the use of a reducing agent, all conducted in toluene as the main solvent. Another significant patent involves the development of unsaturated amine salts of HMG-CoA reductase inhibitors. This invention not only details the method of producing these amine salts but also discusses their use in creating pharmaceutically acceptable salts of HMG-CoA reductase inhibitors.
Career Highlights
Throughout her career, Bessembinder has worked with prominent companies in the pharmaceutical sector. She has been associated with Dsm Sinochem Pharmaceuticals Netherlands B.V. and Centrient Pharmaceuticals Netherlands B.V. Her work in these organizations has allowed her to contribute to innovative pharmaceutical solutions.
Collaborations
Bessembinder has collaborated with several professionals in her field, including Ben De Lange and Dennis Heemskerk. These collaborations have further enhanced her research and development efforts in the pharmaceutical industry.
Conclusion
Karin Henderika Maria Bessembinder is a distinguished inventor whose work has significantly advanced the field of pharmaceuticals. Her innovative patents and collaborations reflect her commitment to improving healthcare through scientific research.