This inventor holds 1 USPTO granted patent. Top assignees: Chu De Nantes, Cnrs (Centre National De La Recherche Scientifique), Hcs Pharma. Active years: 2026.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
1 out of 2 
1 out of 1 
1 out of 1 Years Active: 2026
Title: Karim Si-Tayeb and Liver Organoid Innovation.
Introduction
Karim Si-Tayeb is an inventor associated with Nantes, France. His patent work concerns methods for producing liver organoids, three-dimensional models designed to reproduce important features of liver tissue.
Latest Patents
The patent “Liver organoid manufacturing methods, liver organoids obtained with the same, and uses thereof” describes a process for preparing liver organoids from stem cells. It combines suitable cell-culture media and a three-dimensional porous scaffold with alternating periods of hypoxic and normoxic conditions. The resulting organoids include hepatocytes, cholangiocytes, stellate cells, and sinusoidal endothelial cells. According to the patent description, they express liver-specific genes, respond to LDL internalization, accumulate lipids, and show strong CYP enzyme activity. Si-Tayeb is associated with 1 patent.
Career Highlights
Si-Tayeb is associated with the Institut National de la Santé et de la Recherche Médicale (Inserm) and Nantes Université. His patent reflects research into liver organoid production and potential applications of these models.
Collaborations
His listed coworkers include Amandine Caillaud and Nathalie Maubon.
Conclusion
Karim Si-Tayeb’s patent focuses on a method for creating functional liver organoids, connecting his work in Nantes with research at Inserm and Nantes Université.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile