This inventor holds 1 USPTO granted patent, plus 1 CIPO patent. Top assignee: Universitè Laval. Active years: 2011.
Company Filing History:
Years Active: 2011
Title: The Innovations of Karim Ghani
Introduction
Karim Ghani is a notable inventor based in Québec, Canada. He has made significant contributions to the field of gene therapy through his innovative work on retroviral packaging cells. His research focuses on developing safer and more efficient methods for producing recombinant retroviruses.
Latest Patents
Karim Ghani holds a patent for "High-titer retroviral packaging cells." This invention relates to non-replicative recombinant retrovirus packaging cells that can grow in suspension in a serum-free medium. Specifically, it involves a human embryonic 293SF-based cell line that stably expresses gag and pol gene products from the murine Moloney leukemia virus (MLV) and either the feline RD114 env gene, the gibbon ape leukemia virus (GLV) env gene, or the amphotropic 4070A env gene. This combination allows for the production of high titers of non-replicative retrovirus pseudotypes and prevents the recombination of plasmids. The recombinant retroviruses produced from these cells are safer and easier to produce for clinical use in gene therapy. He has 1 patent to his name.
Career Highlights
Karim Ghani is affiliated with Université Laval, where he continues to advance his research in the field of gene therapy. His work has garnered attention for its potential applications in clinical settings, particularly in improving the safety and efficacy of gene therapy treatments.
Collaborations
Karim collaborates with various professionals in his field, including his coworker Manuel Caruso. Their combined expertise contributes to the advancement of innovative solutions in gene therapy.
Conclusion
Karim Ghani's contributions to the field of gene therapy through his innovative patent on retroviral packaging cells highlight his role as a significant inventor. His work not only enhances the safety of gene therapy but also paves the way for future advancements in the field.