Karen Sommer

Title: The Innovative Contributions of Karen Sommer

Introduction

Karen Sommer is a prominent inventor based in Seattle, WA (US). She has made significant contributions to the field of biotechnology, particularly in the development of novel cellular technologies. With a total of 2 patents, her work focuses on enhancing cell resistance and gene regulation.

Latest Patents

One of her latest patents involves the creation of rapamycin-resistant cells. This application relates to compositions that include proteins designed for expression in host cells, rendering them resistant to rapamycin. The invention also outlines methods for utilizing these proteins, cells, and compositions to modulate cell signaling and selectively expand cells. Another notable patent concerns the expression of FOXP3 in edited CD34+ cells. This invention describes the incorporation of a FOXP3 cDNA into a FOXP3 gene or a non-FOXP3 locus, facilitating regulated FOXP3 expression in primary human CD34 cells or cells derived from edited CD34 cells. The application also discusses the use of guide RNA sequences for CRISPR/Cas9-mediated gene regulation.

Career Highlights

Karen Sommer is affiliated with Seattle Children's Hospital, where she continues to advance her research and innovations. Her work has garnered attention for its potential applications in medical therapies and cellular engineering.

Collaborations

Throughout her career, Karen has collaborated with esteemed colleagues, including Andrew M Scharenberg and David J Rawlings. These partnerships have further enriched her research and contributed to the success of her inventions.

Conclusion

Karen Sommer's innovative work in biotechnology exemplifies the impact of dedicated inventors in advancing medical science. Her patents reflect a commitment to improving cellular technologies and enhancing therapeutic options.