Karen Jean Froning

Title: The Innovations of Karen Jean Froning

Introduction

Karen Jean Froning, an accomplished inventor based in San Diego, California, has made significant contributions to the field of biotechnology. Holding three patents, her work primarily focuses on the development of IgG bispecific antibodies, which have important implications for therapeutic applications.

Latest Patents

One of her notable inventions is titled "IgG bispecific antibodies and processes for preparation." This patent presents a groundbreaking method for creating fully engineered IgG bi-specific antibodies that incorporate designed residues in the interface of the heavy chain-heavy chain domains. The invention also outlines processes for preparing these antibodies, along with the necessary nucleic acids, vectors, and host cells that encode them.

Another significant patent is "Methods for producing Fabs and IgG bispecific antibodies." This innovation provides comprehensive methods for producing Fabs and IgG bispecific antibodies by expressing nucleic acids that encode specifically designed residues in the CH1/CL interface. This not only enhances the production process but also yields effective Fabs and IgG bispecific antibodies, supported by relevant nucleic acids, vectors, and host cells.

Career Highlights

Throughout her career, Karen has been associated with prestigious organizations, including Eli Lilly and Company and the University of North Carolina at Chapel Hill. Her work with these institutions has allowed her to advance her research and refine her innovations in the field of biopharmaceuticals.

Collaborations

Karen has collaborated with esteemed professionals in her field, such as Stephen John Demarest and Brian Arthur Kuhlman. These partnerships have fostered a productive research environment, leading to groundbreaking advancements in antibody development.

Conclusion

In summary, Karen Jean Froning's innovative work in the realm of IgG bispecific antibodies positions her as a pivotal figure in biotechnology. Her patents reflect her dedication to advancing medical science through collaboration and ingenuity, contributing to the ongoing evolution of therapeutic solutions.