This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignee: Regents of the University of Minnesota. Active years: 2015-2017.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2015-2017
Title: The Innovative Contributions of Karen Hsiao Ashe
Introduction
Karen Hsiao Ashe is a prominent inventor based in North Oaks, MN (US). She has made significant contributions to the field of tauopathy research, with a focus on developing compositions and methods that can aid in the diagnosis and treatment of this condition. Her work has led to the filing of two patents, showcasing her innovative approach to addressing complex medical challenges.
Latest Patents
Ashe's latest patents revolve around compositions and methods related to tauopathy. These patents disclose isolated polypeptides, antibody preparations, treatment methods, diagnostic methods, and screening methods. The isolated polypeptides include a core pentapeptide, ensuring that they are not native full-length tau proteins. The antibody preparations are designed to specifically bind to SEQ ID NO:12. The treatment methods involve administering a composition that includes the isolated polypeptide to a subject. Furthermore, the diagnostic methods entail contacting a sample from a subject with an antibody preparation that binds to SEQ ID NO:12, followed by detecting a ligand in the sample that interacts with the antibody preparation. The screening method includes incubating a mixture of caspase-2, a labeled caspase-2 cleavage substrate, and a test compound to determine whether the test compound inhibits the cleavage of the substrate by caspase-2.
Career Highlights
Karen Hsiao Ashe is affiliated with the University of Minnesota, where she continues her research and innovation in the field of tauopathy. Her work has garnered attention for its potential impact on understanding and treating neurodegenerative diseases.
Collaborations
Ashe collaborates with notable colleagues, including Xiaohui Zhao and Michael Anthony Walters, who contribute to her research endeavors and enhance the collaborative spirit of innovation within her team.
Conclusion
Karen Hsiao Ashe's contributions to the field of tauopathy research exemplify her dedication to innovation and her commitment to improving medical outcomes. Her patents reflect a significant advancement in the understanding and treatment of tau-related conditions.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile