Company Filing History:
2 out of 6,850 
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Years Active: 1994-1998
Title: Karel Gerrit Odink: Innovator in Inflammatory Mediators
Introduction
Karel Gerrit Odink is a notable inventor based in Rheinfelden, Switzerland. He has made significant contributions to the field of biotechnology, particularly in the development of polypeptides that mediate inflammation. With a total of 6 patents to his name, Odink's work has implications for therapeutic and diagnostic methods in various medical conditions.
Latest Patents
One of his latest patents involves a cytokine that mediates inflammation. This invention concerns polypeptides with an apparent molecular weight of around 160 kD, which serve as mediators or precursors for mediators of inflammation. The patent also covers derivatives such as mutants and fragments, processes for their preparation, DNAs and hybrid vectors coding for these polypeptides, and host cells transformed with such hybrid vectors. Additionally, it includes polyclonal and monoclonal antibodies specific for the polypeptides or their derivatives, along with diagnostic and therapeutic methods for inflammatory conditions and Hodgkin lymphomas.
Another significant patent focuses on DNAs encoding human macrophage migration inhibition factor related polypeptides, specifically MRP-8 and MRP-14. This invention encompasses processes for their preparation, mRNAs, DNAs, and hybrid vectors coding for these polypeptides, as well as hosts transformed with such hybrid vectors. It also includes monoclonal and polyclonal antibodies to these polypeptides and diagnostic methods for inflammatory conditions and cystic fibrosis.
Career Highlights
Throughout his career, Karel Gerrit Odink has worked with prominent companies in the pharmaceutical industry, including Ciba-Geigy Corporation and Novartis Corporation. His experience in these organizations has contributed to his expertise in the field of biotechnology and patent development.
Collaborations
Odink has collaborated with notable colleagues such as Nico Cerletti and Josef Bruggen, further enhancing his contributions to the field.
Conclusion
Karel Gerrit Odink's innovative work in the development of polypeptides related to inflammation has positioned him as a key figure in biotechnology. His patents not only advance scientific understanding but also hold promise for future therapeutic applications.