Location History:
- D.D.O., CA (1997)
- Quebec, CA (1999)
- Dollard des Ormeaux, CA (2000)
Company Filing History:
Years Active: 1997-2000
Title: **Kangfu Gu: A Pioneer in Chondroitin Lyase Enzymes**
Introduction
Kangfu Gu is an innovative inventor based in Dollard des Ormeaux, Canada, known for his remarkable contributions to the field of biotechnology. With a total of four patents to his name, Gu has made significant strides in the production of enzymes that play a crucial role in degrading chondroitin sulfate polysaccharides.
Latest Patents
His latest patents focus on chondroitin lyase enzymes, where he outlines a comprehensive method for producing highly purified enzymes. These enzymes are capable of degrading chondroitin sulfates A and C as well as dermatan sulfate. The invention details a multi-step purification process that includes cell disruption, cation exchange chromatography, affinity chromatography, hydroxylapatite chromatography, high-resolution ion exchange chromatography, and size exclusion. This innovative approach has led to the isolation of two key proteins: a 77,000 ± 5,000 Dalton protein and a 55,000 ± 2,300 Dalton protein, both of which are vital for their intended applications. The genes encoding these enzymes, chondroitinase AC and chondroitinase B, have also been successfully cloned, and methods for their application are thoroughly described within the patents.
Career Highlights
Throughout his career, Kangfu Gu has worked with notable organizations, including Ibex Technologies R&D, Inc. and Ibex Technologies Ltd. His expertise in the development and purification of enzymes has made him a valuable asset in the biotechnology sector.
Collaborations
Gu has collaborated with esteemed colleagues, including Joseph J. Zimmermann and D. Clark Bennett. Their teamwork and combined expertise have propelled advancements in enzyme technology, highlighting the importance of collaboration in scientific innovation.
Conclusion
Kangfu Gu’s contributions to the field of biotechnology, particularly in the development of chondroitin lyase enzymes, exemplify the impact of innovation in science. His patents not only showcase his technical skill but also pave the way for potential advancements in therapeutic applications related to chondroitin sulfate degradation. With his continued dedication to research and innovation, Gu remains a significant figure in the quest for biotechnological advancements.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.