Kae-Shyang Shih

Title: Kae-Shyang Shih: Innovator in Peptide-Synthesis Technologies

Introduction

Kae-Shyang Shih is a prominent inventor based in Taipei, Taiwan. He has made significant contributions to the field of biotechnology, particularly in the synthesis of peptide-spacer-lipid conjugates. With a total of 2 patents, his work has implications for drug delivery systems and pharmaceutical processes.

Latest Patents

Kae-Shyang Shih's latest patents include a solid phase method for synthesizing peptide-spacer-lipid conjugates and a process for preparing fluconazole. The first patent describes a convenient solid phase synthesis method that simplifies the preparation of peptide-spacer-lipid conjugates. This method allows for automation and easier purification, minimizing product loss during synthesis. The conjugates can be incorporated into liposomes for targeted drug delivery to specific cells. The second patent outlines a multi-step process for synthesizing fluconazole, which involves acylating 1,3-difluorobenzene and alkylating 4-amino-4H-1,2,4-triazole.

Career Highlights

Kae-Shyang Shih is affiliated with the Development Center for Biotechnology, where he continues to advance research in biopharmaceuticals. His innovative approaches have garnered attention in the scientific community, contributing to the development of more effective drug delivery systems.

Collaborations

Some of his notable coworkers include Lie-Rong Chen and Ching-Wei Liu, who have collaborated with him on various projects within the biotechnology sector.

Conclusion

Kae-Shyang Shih's contributions to peptide synthesis and drug delivery systems highlight his role as a key innovator in biotechnology. His patents reflect a commitment to advancing pharmaceutical technologies for improved healthcare solutions.