Location History:
- Laguna Hill, CA (US) (2001 - 2009)
- Laguna Hills, CA (US) (2005 - 2011)
- Coto de Caza, CA (US) (2007 - 2013)
- Irvine, CA (US) (2015)
Company Filing History:
22 out of 2,285 
2 out of 228 
1 out of 36 
Years Active: 2001-2015
Title: K Roger Aoki: A Pioneer in Pain Treatment Innovations
Introduction
K Roger Aoki, located in Coto de Caza, California, is a notable inventor with an impressive portfolio of 25 patents. His contributions to medical science, particularly in the realm of pain treatment, have garnered significant attention and acclaim in various industries.
Latest Patents
Aoki's latest patents demonstrate his innovative approach to treating pain. One such patent focuses on the use of a therapeutic molecule designed to address specific pain conditions. This therapeutic molecule is a single chain, polypeptide fusion protein that incorporates a non-cytotoxic protease capable of cleaving a protein of the exocytic fusion apparatus of nociceptive sensory afferents. The design includes a Targeting Moiety that binds to a specific Binding Site on the nociceptive sensory afferent, which can undergo endocytosis to incorporate into an endosome. Additionally, the patent specifies a protease cleavage site that allows for the fusion protein to be cleaved, along with a translation domain facilitating the translocation of the protease into the cytosol of the nociceptive sensory afferent. Another notable patent addresses botulinum toxin treatments, detailing a method for administering a therapeutically effective amount of neurotoxins for treating patients suffering from various disorders and associated pain.
Career Highlights
Throughout his career, K Roger Aoki has contributed to significant advancements in the pharmaceutical and medical device industries. He has worked with leading companies such as Allergan, Inc. and Allergan Sales, Inc., where he played a pivotal role in the development and commercialization of innovative pain management therapies. His expertise in biopharmaceuticals has established him as a key figure in the field.
Collaborations
Collaboration plays a crucial role in Aoki's work. He has partnered with renowned coworkers such as Michael W. Grayston and Judith M. Leon, contributing to the advancement of pain treatment methodologies and enhancing the effectiveness of therapeutic interventions.
Conclusion
K Roger Aoki’s contributions to pain management innovations have marked him as a leading inventor in the industry. With a robust portfolio of patents, extensive career experience, and effective collaborations, Aoki continues to push the boundaries of science and medicine, providing hope and relief to countless patients suffering from pain-related conditions.