Company Filing History:
Years Active: 1985-1986
Title: The Innovative Contributions of K Ming Wan in Chemical Engineering
Introduction
K Ming Wan, an accomplished inventor based in East Brunswick, NJ, has made significant strides in the field of chemical engineering. With a portfolio that includes three innovative patents, Wan's contributions are poised to impact the synthesis of key chemical compounds, particularly in the food industry.
Latest Patents
One of K Ming Wan’s notable patents focuses on the **Preparation of Large Crystals of N-Benzyloxycarbonyl-L-Aspartic Acid**. This invention introduces a method to create N-Benzyloxycarbonyl-L-Aspartic acid (Z-Asp) crystals that are several times larger than those produced through conventional crystallization methods. By acidifying an alkaline aqueous solution of a metal salt of Z-Asp at high temperatures (between approximately 20°C to 45°C), the resulting large crystals exhibit lower moisture and fewer impurities such as sodium chloride, dipeptide, and benzyl alcohol. This advancement significantly enhances the processing efficiency for preparing aspartame.
Another significant contribution by Wan is the **Synthesis of N-Benzyloxycarbonyl-L-Aspartic Acid**. This patent outlines a method for synthesizing Z-Asp by adding benzyl chloroformate to a solution of L-aspartic acid and sodium hydroxide at elevated temperatures (35°C to 55°C) and a broad pH range of 9.2 to 12.0. The synthesis produces high yields exceeding 90% and a purity greater than 99%, with minimal by-products. The high-temperature reactions not only accelerate the cycle time but also maintain a high yield while minimizing dipeptide and unreacted L-aspartic acid contents.
Career Highlights
K Ming Wan is currently employed at Hatco Chemical Corporation, where he continues to push the boundaries of chemical innovation. His work significantly contributes to the company's mission of developing high-quality chemical compounds for various applications, particularly in the food industry.
Collaborations
Throughout his career, Wan has collaborated with talented individuals such as Mary S Chen and Clay T Chen. These collaborations have fostered an environment of innovative thinking and have significantly aided in the advancement of their collective research endeavors.
Conclusion
K Ming Wan's contributions to the field of chemical engineering through his innovative patents exemplify the positive impact of his work within the industry. His advancements in the preparation and synthesis of crucial compounds like N-Benzyloxycarbonyl-L-Aspartic acid not only showcase his expertise but also pave the way for future innovations in food manufacturing and quality. As he continues his work at Hatco Chemical Corporation, the potential for further breakthroughs remains promising, solidifying his legacy as a notable inventor in his field.