Company Filing History:
Years Active: 1992-2000
Title: Innovator Jyotsna S Shah: Pioneering Advances in Nucleic Acid Detection
Introduction: Jyotsna S Shah is an accomplished inventor based in Nashua, NH, USA, known for her significant contributions to the field of molecular biology. With a portfolio of 13 patents, Shah has made remarkable advancements, particularly in methods for detecting target nucleic acid fragments, which are crucial for diagnosing various pathogens.
Latest Patents: Among her latest inventions, the insitu hybridization method stands out. This innovative technique allows for the direct detection of target nucleic acid fragments from patient specimens through a detailed process. The method involves depositing a sample on a slide, fixing it, and using specific probe complexes under optimal conditions for hybridization. Following this, non-hybridized probe complexes are rinsed away, and the sample is stained for visual detection via microscopy, indicating the presence of the target nucleic acid fragment. This method is particularly invaluable for detecting pathogens such as those from the species Babesia, and it is adaptable for various specimen types including serum, plasma, urine, and even insects like ticks. Additionally, her work encompasses the development of nucleic acid probes for detecting Pneumocystis carinii in hybridization assays.
Career Highlights: Jyotsna has had an influential career with significant roles at reputable companies. She has worked with Amoco Corporation and Norval B. Galloway, contributing to her expertise and experience in the field.
Collaborations: Throughout her career, Jyotsna has collaborated with notable individuals such as David J Lane and Amelia Buharin, who have played a role in her research efforts and innovations.
Conclusion: Jyotsna S Shah exemplifies the spirit of innovation in biotechnology through her influential patents and collaborations. Her dedication to advancing nucleic acid detection has notable implications for medical diagnostics, paving the way for enhanced pathogen detection methods in diverse specimens.
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