Jurgen S Scheele

Title: **Innovator Jurgen S. Scheele: A Pioneer in G Protein Research**

Introduction

Jurgen S. Scheele, based in Del Mar, California, is a notable inventor recognized for his contribution to the field of biochemistry. His innovations focus particularly on G protein interactions, which play a crucial role in various cellular processes.

Latest Patents

Scheele holds a significant patent titled "Method of quantitating GTP and GDP bound to a G protein and uses thereof." This invention provides methodologies for measuring the total amounts of G protein-bound GDP and GTP in mammalian cells and tissues. The method is particularly advantageous compared to conventional techniques, as it eliminates the need for phosphate-free growth conditions that could compromise GTP measurement accuracy. Furthermore, his method does not require radiolabelled phosphate exposure, thus providing a more streamlined and reliable approach. The standardized quantification of G protein-bound GDP and GTP allows for comparisons across various cell types, particularly aiding in the detection of Ras protein-bound GTP and GDP. This innovation has profound implications for understanding cellular processes related to diseases, hormonal secretion, cellular differentiation, and more.

Career Highlights

Throughout his career, Jurgen S. Scheele has contributed to esteemed organizations, including the Mount Sinai Hospital Corporation and the University of California. His work has been essential in advancing scientific understanding in his field.

Collaborations

Jurgen has worked alongside notable colleagues such as Gerry R. Boss and Abhijit Guha. These collaborations have further expanded the impact of his research and innovative methods within the scientific community.

Conclusion

Jurgen S. Scheele's contributions to the understanding of G protein interactions mark a significant advancement in biochemical research. His patented methods not only enhance measurement accuracy but also provide valuable insights into cellular functions and diseases. As his research continues to influence the field, he stands as a prominent figure among inventors in biochemistry.