This inventor holds 1 USPTO granted patent and 2 published patent applications. Top assignee: The Cleveland Clinic Foundation. Active years: 2017.
Company Filing History:
Years Active: 2017
Title: Innovations of Junpeng Deng in Treating IL-17 Mediated Diseases
Introduction
Junpeng Deng is an accomplished inventor based in Cleveland, OH (US). He has made significant contributions to the field of medical treatments, particularly in addressing IL-17 mediated diseases. His innovative approach focuses on utilizing decoy peptides to inhibit specific protein interactions, which can lead to effective therapies for various inflammatory and autoimmune conditions.
Latest Patents
Junpeng Deng holds 1 patent for his work titled "Treatment of IL-17 mediated disease by blocking SEFIR-SEFIR interactions." This patent describes a method of treating IL-17 mediated diseases by administering a therapeutically effective amount of a cell-permeable decoy peptide. This peptide competitively inhibits the binding of the SEFIR domain of IL-17R to the SEFIR domain of Act1. The research highlights the critical role of the αC helix region of the SEFIR domain in the association of IL-17R and Act1. To enhance cell permeation, the decoy peptide is preferably conjugated to a protein transduction domain. Examples of IL-17 mediated diseases include various human and animal inflammatory and autoimmune diseases, such as asthma.
Career Highlights
Junpeng Deng is affiliated with The Cleveland Clinic Foundation, where he continues to advance his research and innovations. His work is pivotal in developing new therapeutic strategies that can significantly improve patient outcomes in the realm of inflammatory diseases.
Collaborations
He collaborates with esteemed colleagues, including Thomas A. Hamilton and Xiaoxia Li, who contribute to the research and development of his innovative treatments.
Conclusion
Junpeng Deng's contributions to the treatment of IL-17 mediated diseases exemplify the impact of innovative research in medicine. His patented methods offer promising avenues for addressing complex health challenges.