Company Filing History:
Years Active: 2000
Title: June W Klimash: Innovator in Dendritic Polymers
Introduction
June W Klimash is a notable inventor based in Midland, MI (US). She has made significant contributions to the field of dendritic polymers, particularly through her innovative patent related to disulfide-containing dendritic polymers. Her work has implications in various applications, including drug delivery and diagnostics.
Latest Patents
June W Klimash holds a patent for "Disulfide-containing dendritic polymers." This invention involves dendritic polymers that contain disulfide functional groups, which remain inert under non-reducing conditions but can form sulfhydryl groups when subjected to a reducing agent. The synthesis of these polymers can be achieved by creating dendritic polymers with a core featuring a disulfide linkage or by reacting a dendritic polymer with a molecule that has a disulfide linkage and reactive terminal groups. The invention also includes dendritic polymers with a single disulfide functional group at the core, which can be reduced to yield two sulfhydryl groups. These groups can bind to various molecules, including proteins and oligonucleotides. The applications of her invention extend to the formation of differentiated dendrimers, binding reagents for diagnostics, drug delivery, gene therapy, and the preparation of self-assembled dendrimer monolayers.
Career Highlights
June W Klimash is associated with Dendritech Inc., where she has been able to apply her expertise in dendritic polymers. Her innovative work has led to advancements in the field, showcasing her ability to merge scientific research with practical applications.
Collaborations
Throughout her career, June has collaborated with notable colleagues, including Herbert M Brothers, II and Douglas R Swanson. These collaborations have likely contributed to her success and the development of her patented technologies.
Conclusion
June W Klimash is a pioneering inventor whose work in dendritic polymers has opened new avenues for research and application in various fields. Her contributions continue to impact the scientific community and beyond.