Location History:
- Danbury, CT (US) (2007 - 2012)
- Ridgefield, CT (US) (2016)
Company Filing History:
4 out of 276 
2 out of 1,536 
1 out of 1,327 
Years Active: 2007-2016
Title: Jun Li: Innovator in Cell-Cell Fusion Modulation
Introduction
Jun Li is a prominent inventor based in Danbury, CT (US), known for his significant contributions to the field of cell biology. He holds a total of 6 patents that focus on innovative methods and compositions for modulating cell-cell fusion, particularly in relation to various diseases and disorders.
Latest Patents
Among his latest patents, one notable invention is titled "Compositions and methods for modulating cell-cell fusion via intermediate-conductance calcium-activated potassium channels." This patent provides compositions and methods for modulating cell-cell fusion by using agents that influence the expression, activity, or function of the SK4 channel. The invention aims to inhibit multi-nucleated osteoclastogenesis and cell-cell fusion, especially involving macrophages. The compositions can include inhibitory nucleic acids, monoclonal antibodies, or small molecule inhibitors of the SK4 channels, which may be useful in treating conditions such as bone loss, autoimmune diseases, and cancer metastasis. Another significant patent is related to "T cell proteins and nucleotides encoding the same," which focuses on mouse and human J12 polynucleotides and polypeptides. The J12 cytokine is preferentially expressed in Th2 cells and can be utilized in the detection and treatment of autoimmune and inflammatory diseases, including asthma.
Career Highlights
Jun Li has worked with notable companies in the pharmaceutical industry, including Boehringer Ingelheim Pharmaceuticals, Inc. and Boehringer Ingelheim International GmbH. His work in these organizations has contributed to advancements in medical research and therapeutic development.
Collaborations
Throughout his career, Jun Li has collaborated with esteemed colleagues, including Xiang Li and Jianfei Yang. These collaborations have fostered innovation and the sharing of knowledge in the field of cell biology.
Conclusion
Jun Li's innovative work in modulating cell-cell fusion has the potential to impact the treatment of various diseases significantly. His contributions to the field are marked by a commitment to advancing medical science through his patents and collaborations.