This inventor holds 3 USPTO granted patents and 3 published patent applications. Top assignee: National Yang Ming Chiao Tung University. Active years: 2016-2019.
Location History:
- Hsinchu, TW (2016)
- Hsinchu County, TW (2018)
- Zhubei, TW (2019)
Company Filing History:
Years Active: 2016-2019
Title: Jui-I Chao: Innovator in Pharmaceutical Composition and Cancer Therapy
Introduction
Jui-I Chao is a notable inventor based in Zhubei, Taiwan. He has made significant contributions to the field of pharmaceuticals, particularly in the development of compositions aimed at treating malignant tumors associated with specific genetic mutations. With a total of 3 patents, his work is paving the way for innovative cancer therapies.
Latest Patents
One of Jui-I Chao's latest patents involves a pharmaceutical composition that includes a 4-anilinoquinazoline derivative. This composition is designed to prevent, treat, or ameliorate symptoms of malignant tumors associated with EGFR and K-RAS mutations. The formula (I) of this derivative is crucial for its effectiveness. Another significant patent focuses on a method for overcoming drug resistance in non-small cell lung carcinoma (NSCLC) caused by the EGFR mutation (T790M). This method introduces SP101, a novel gefitinib derivative that binds to the ATP-binding pocket of EGFR, inhibiting its kinase activity. SP101 has shown promise in reducing drug resistance and inducing cancer cell death in gefitinib-resistant H1975 cells.
Career Highlights
Jui-I Chao is affiliated with National Yang Ming Chiao Tung University, where he conducts research and develops innovative pharmaceutical solutions. His work is characterized by a strong focus on addressing the challenges posed by drug resistance in cancer treatment.
Collaborations
Jui-I Chao collaborates with esteemed colleagues, including Kuang-Kai Liu and Su-Pei Wang, who contribute to his research endeavors. Their combined expertise enhances the potential impact of their work in the field of cancer therapy.
Conclusion
Jui-I Chao's innovative contributions to pharmaceutical compositions and cancer treatment exemplify the importance of research in overcoming medical challenges. His patents reflect a commitment to improving patient outcomes in the fight against cancer.