Company Filing History:
Years Active: 2025
Title: Jui Dutta-Simmons: Innovator in Circular RNA Technology
Introduction
Jui Dutta-Simmons is an accomplished inventor based in Watertown, MA (US). He has made significant contributions to the field of biotechnology, particularly in the development of circular RNA technologies. His innovative work has the potential to advance therapeutic applications in various medical fields.
Latest Patents
Jui Dutta-Simmons holds a patent for "Circular RNA encoding chimeric antigen receptors targeting BCMA." This patent describes circular RNA along with related compositions and methods. The inventive circular RNA comprises group I intron fragments, spacers, an IRES, duplex forming regions, and an expression sequence. In some embodiments, the expression sequence encodes an antigen. The circular RNA of the invention demonstrates improved expression, functional stability, immunogenicity, ease of manufacturing, and half-life when compared to linear RNA. Additionally, the methods and constructs result in enhanced circularization efficiency, splicing efficiency, and purity compared to existing RNA circularization approaches. He has 1 patent to his name.
Career Highlights
Jui Dutta-Simmons is currently associated with Orna Therapeutics, Inc., where he continues to push the boundaries of RNA technology. His work is pivotal in the ongoing research and development of innovative therapeutic solutions.
Collaborations
Jui collaborates with notable colleagues, including Thomas Barnes and Amy M Becker, who contribute to the dynamic research environment at Orna Therapeutics, Inc.
Conclusion
Jui Dutta-Simmons is a leading figure in the field of circular RNA technology, with a focus on developing innovative solutions for medical applications. His contributions are shaping the future of biotechnology and therapeutic development.