Helsinki, Finland

Juha Kaivola


Average Co-Inventor Count = 7.2

ph-index = 3

Forward Citations = 27(Granted Patents)


Company Filing History:


Years Active: 1999-2004

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6 patents (USPTO):Explore Patents

Title: Juha Kaivola: Innovator in Phospholamban Inhibitors

Introduction

Juha Kaivola is a prominent inventor based in Helsinki, Finland. He has made significant contributions to the field of drug design, particularly in the development of compounds that target phospholamban function. With a total of 6 patents to his name, Kaivola's work is paving the way for advancements in treatments for heart conditions.

Latest Patents

One of his latest patents focuses on compounds for deactivating phospholamban function on Ca-ATPase, specifically phospholamban inhibitors. This invention involves determining the three-dimensional structure of the cytosolic domain of phospholamban (PLB) and its active site using high-resolution NMR data. The invention also encompasses methods for rational drug design, enabling the creation of phospholamban inhibitors based on the three-dimensional structure data analyzed through suitable computer algorithms. Additionally, it includes phospholamban inhibiting compounds with specific structural, physicochemical, and spatial characteristics that facilitate interaction with the active site of phospholamban.

Another notable patent involves pyridazinyl phenyl hydrazones, which are useful against congestive heart failure. These innovations highlight Kaivola's commitment to addressing critical health issues through scientific research and development.

Career Highlights

Juha Kaivola is associated with Orion Corporation, a company known for its focus on pharmaceuticals and innovative healthcare solutions. His work at Orion has allowed him to contribute to significant advancements in drug development, particularly in cardiovascular health.

Collaborations

Throughout his career, Kaivola has collaborated with esteemed colleagues, including Heimo O Haikala and Piero Pollesello. These partnerships have fostered a collaborative environment that enhances the research and development process.

Conclusion

Juha Kaivola's innovative work in the field of phospholamban inhibitors and drug design exemplifies the impact of dedicated research on healthcare advancements. His contributions continue to inspire future innovations in the pharmaceutical industry.

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